Research in Vestibular Science

Case Reports

A Case of Tumarkin Otolithic Crisis Treated with Intratympanic Gentamicin Injection: Soo Hyun Joo, Hong-Ju Kim, Hyun-Ji Kim, Kyu-Sung Kim; Res Vestib Sci. 2020;19(1):22-28. Published online March 15, 2020; DOI: https://doi.org/10.21790/rvs.2020.19.1.22

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Abstract PDF: Tumarkin otolithic crisis is an abrupt attack of falling without loss of consciousness because of peripheral vestibular disorders. It occurs without warning in patients with late stage or end-stage of Meniere’s disease. It is an otologic emergency due to the risk of fall down injury, and has been treated with labyrinthectomy, vestibular neurectomy, and intratympanic gentamicin injection. Many reports have reported the efficacy of intratympanic injection of gentamicin (ITIG) as chemical ablation. We report a 58-year-old man with Tumarkin otolothic crisis from Meniere’s disease who presented with sudden drop attack while driving a taxi. He has suffered from recurrent rotatory vertigo accompanied by fluctuating hearing loss and tinnitus in the right ear for years. Despite medical treatment over the next 2 months, he experienced three more sudden drop attacks. He got chemical ablation with ITIG and remains without sudden drop attack until fourteen months later. Tumarkin otolithic crisis is a life-threatening otologic emergency. What we have experienced in this case is that for the safety and quality of life of the patient who suffers from Tumarkin otolithic crisis, aggressive vestibular function ablation with high dose ITIG is necessary.

Autoimmune Inner Ear Disease Mimicking Bilateral Ménièreʼs Disease: A Case Report: Hong-Ju Kim, Yoon-Gi Choi, Hyun Ji Kim, Kyu-Sung Kim; Res Vestib Sci. 2018;17(1):28-34. Published online March 15, 2018; DOI: https://doi.org/10.21790/rvs.2018.17.1.28

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Autoimmune inner ear disease (AIED) is a rare disease, accounting for <1% of all cases of hearing impairment or dizziness. It is characterized by sensorineural hearing loss (SNHL) or vestibular dysfunction that results from an immunemediated process. Clinical features of AIED is SNHL that progresses over weeks to month with fluctuating hearing symptoms. Because there are no diagnostic laboratory and clinical feature, response to immunosuppressive therapy were important for diagnosis of AIED. Many diseases such as sudden SNHL and Meniere disease may also mimic AIED, a broad differential must be maintained in patients suspected of having AIED. We report a case of a 46-year-old female who presented with sudden hearing loss and vertigo. We could diagnose her as AIED with systemic lupus erythematous. The symptoms were improved treated with steroids.

Citations

Citations to this article as recorded by

Sensorineural Hearing Loss of Suspected Autoimmune Etiology: Two Cases of Cogan’s Syndrome
Jungmin Ahn, Brian Kim, Kyoung Rai Cho, Young-Soo Chang
Korean Journal of Otorhinolaryngology-Head and Nec.2021; 64(12): 943. CrossRef
A Case of Autoimmune Sensorineural Hearing Loss Responding to Cytotoxic Agent
Yong Woo Lee, Jin Lee, Min-Beom Kim, Sun O Chang
Korean Journal of Otorhinolaryngology-Head and Nec.2019; 62(8): 470. CrossRef

A Case of Autoimmune Inner Ear Disease Mimicking Bilateral Ménièreʼs Disease: Hong-Ju Kim, Yoon-Gi Choi, HyunJi Kim, Kyu-Sung Kim; Received February 1, 2018 Accepted March 8, 2018 Published online March 8, 2018; [Accepted]

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Abstract: Autoimmune inner ear disease(AIED) is a rare disease, accounting for <1% of all case of hearing impairment or dizziness. It is characterized by sensorineural hearing loss(SNHL) or vestibular dysfunction that result from an immune-mediated process. Clinical feature of AIED is SNHL that progresses over weeks to months and fluctuating hearing symptoms. Because there’s no diagnostic laboratory test, clinical features and re-sponse to immunosuppressive therapy were important for diagnosis of AIED. Many disease such as sudden sensorineural hearing loss and Meniere's disease may also mimic AIED, a broad differential must be maintained in patients suspected of having AIED. We report a case of a 46-year-old female who presented with sudden hearing loss and vertigo. We could diagnose her as AIED with systemic lupus erythematous(SLE). The symptoms were improved treated with steroids.

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